| 1 | Robert Lewandowski
FC Barcelona | FC Barcelona | 31 | 25 |
| 2 | Kylian Mbappé
Real Madrid | Real Madrid | 29 | 22 |
| 3 | Ante Budimir
Osasuna | Osasuna | 32 | 18 |
| 4 | Oihan Sancet
Athletic Bilbao | Athletic Bilbao | 24 | 15 |
| - | Rafinha
FC Barcelona | FC Barcelona | 31 | 15 |
| 6 | Ayoze Pérez
Villarreal CF | Villarreal CF | 24 | 14 |
| - | Julián Álvarez
Atlético Madrid | Atlético Madrid | 32 | 14 |
| 8 | Alexander Sørloth
Atlético Madrid | Atlético Madrid | 29 | 12 |
| - | Kike
Alavés | Alavés | 30 | 12 |
| 10 | Vinícius Júnior
Real Madrid | Real Madrid | 26 | 11 |
| - | Javi Puado
RCD Espanyol | RCD Espanyol | 29 | 11 |
| - | Dodi Lukebakio
Sevilla FC | Sevilla FC | 32 | 11 |
| 13 | Ferrán Torres
FC Barcelona | FC Barcelona | 26 | 10 |
| - | Fábio Silva
Las Palmas | Las Palmas | 24 | 10 |
| - | Thierno Barry
Villarreal CF | Villarreal CF | 30 | 10 |
| 16 | Daniel Olmo
FC Barcelona | FC Barcelona | 20 | 9 |
| - | Mauro Wilney Arambarri Rosa
Getafe CF | Getafe CF | 30 | 9 |
| 18 | Iago Aspas
Celta de Vigo | Celta de Vigo | 25 | 8 |
| - | Borja Iglesias
Celta de Vigo | Celta de Vigo | 31 | 8 |
| - | Sandro Ramírez
Las Palmas | Las Palmas | 27 | 8 |
| - | Mikel Oiarzabal
Real Sociedad | Real Sociedad | 29 | 8 |
| - | Hugo Duro Perales
Valencia CF | Valencia CF | 26 | 8 |
| - | Jude Bellingham
Real Madrid | Real Madrid | 26 | 8 |
| - | Antoine Griezmann
Atlético Madrid | Atlético Madrid | 32 | 8 |
| 25 | Cristian Stuani
FC Girona | FC Girona | 26 | 7 |
| - | Giovani Lo Celso
Real Betis | Real Betis | 20 | 7 |
| - | Isco
Real Betis | Real Betis | 16 | 7 |
| - | Daniel Raba
Leganés | Leganés | 23 | 7 |
| - | Vedat Muriqi
RCD Mallorca | RCD Mallorca | 24 | 7 |
| - | Diego López
Valencia CF | Valencia CF | 33 | 7 |
| 31 | Cyle Larin
RCD Mallorca | RCD Mallorca | 27 | 6 |
| - | Gorka Guruzeta
Athletic Bilbao | Athletic Bilbao | 31 | 6 |
| - | Rodrygo
Real Madrid | Real Madrid | 29 | 6 |
| - | Álex Baena
Villarreal CF | Villarreal CF | 27 | 6 |
| - | Alberto Moleiro
Las Palmas | Las Palmas | 30 | 6 |
| - | Lamine Yamal
FC Barcelona | FC Barcelona | 30 | 6 |
| - | Federico Santiago Valverde Dipetta
Real Madrid | Real Madrid | 30 | 6 |
| 38 | Sadiq Umar
Valencia CF | Valencia CF | 12 | 5 |
| - | Roberto Fernandez
RCD Espanyol | RCD Espanyol | 13 | 5 |
| - | Mamadou Sylla Diallo
Real Valladolid | Real Valladolid | 25 | 5 |
| - | Nico Williams
Athletic Bilbao | Athletic Bilbao | 27 | 5 |
| - | Takefusa Kubo
Real Sociedad | Real Sociedad | 30 | 5 |
| - | Álex Berenguer
Athletic Bilbao | Athletic Bilbao | 31 | 5 |
| - | Iñaki Williams
Athletic Bilbao | Athletic Bilbao | 31 | 5 |
| 45 | Borja Mayoral
Getafe CF | Getafe CF | 17 | 4 |
| - | Toni Martínez
Alavés | Alavés | 24 | 4 |
| - | Alfonso González
Celta de Vigo | Celta de Vigo | 21 | 4 |
| - | Pablo Durán
Celta de Vigo | Celta de Vigo | 22 | 4 |
| - | Brahim Abdelkader Díaz
Real Madrid | Real Madrid | 27 | 4 |
| - | Vitor Roque
Real Betis | Real Betis | 22 | 4 |